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Listar por autor "Kontogianni, K."

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    • Associations between BODE Index and Systemic Inflammatory Biomarkers in COPD 

      Gaki, E.; Kontogianni, K.; Papaioannou, A. I.; Bakakos, P.; Gourgoulianis, K. I.; Kostikas, K.; Alchanatis, M.; Papiris, S.; Loukides, S. (2011)
      Background: COPD is a multicomponent disease and systemic inflammation represents one of the possible mechanisms responsible for its systemic manifestations, including skeletal muscle weakness and cachexia. Fat-free mass ...

    • Clinical applications of the comet assay 

      Piperakis, S. M.; Kontogianni, K.; Karanastasi, G.; Piperakis, M. M. (2009)

    • DNA damage and repair capacity in lymphocytes from obstructive sleep apnea patients 

      Kontogianni, K.; Messini-Nikolaki, N.; Christou, K.; Gourgoulianis, K.; Tsilimigaki, S.; Piperakis, S. M. (2007)
      Obstructive sleep apnea (OSA) syndrome is a respiratory disease that is linked to heart attacks and high blood pressure. In the present study, we used the Comet assay to compare basal DNA damage and DNA damage induction ...

    • Effects of pesticides on exposed populations from four European countries 

      Piperakis, S. M.; Kontogianni, K.; Karanastasi, G.; Siffel, C.; Cebulska-Wasilewska, A.; Markos, R.; Iakovidou-Kritsi, Z.; Piperakis, M. M. (2008)
      The potential genetic hazard of pesticides to humans is of great concern, in particular in occupational and environmental settings because of their widespread use for domestic and industrial applications. In the present ...

    • Effects of pesticides on occupationally exposed humans 

      Piperakis, S. M.; Kontogianni, K.; Piperakis, M. M.; Marcos, R.; Tsilimigaki, S. (2006)
      Pesticides are known to contain numerous genotoxic compounds; however, genotoxicity biomonitoring studies of workers occupationally exposed to pesticides have produced variable results. In this study, we employed the Comet ...

    • Exhaled breath condensate in asthma: From bench to bedside 

      Loukides, S.; Kontogianni, K.; Hillas, G.; Horvath, I. (2011)
      The need for non-invasive assessment of airway inflammation is imperative, since inflammatory airway diseases, such as asthma and COPD, are characterized by variation in their clinical presentation throughout their course. ...

    • Exhaled breath condensate pH as a biomarker of COPD severity in ex-smokers 

      Papaioannou, A. I.; Loukides, S.; Minas, M.; Kontogianni, K.; Bakakos, P.; Gourgoulianis, K. I.; Alchanatis, M.; Papiris, S.; Kostikas, K. (2011)
      Endogenous airway acidification, as assessed by exhaled breath condensate (EBC) pH, is present in patients with stable COPD. The aim of this study was to measure EBC pH levels in a large cohort of COPD patients and to ...

    • Investigation of the Genotoxic Effect of Pesticides on Greenhouse Workers' Lymphocytes 

      Piperakis, S. M.; Kontogianni, K.; Karanastasi, G.; Iakovidou-Kritsi, Z.; Cebulska-Wasilewska, A.; Piperakis, M. M. (2009)
      In the present study, the genotoxic effects of commonly applied pesticides were evaluated using the alkaline comet assay (pH > 13). The amount of DNA damage (% DNA in tail) in peripheral lymphocytes of 49 male agricultural ...

    • Measuring the effects of pesticides on occupationally exposed humans with the comet assay 

      Piperakis, S. M.; Kontogianni, K.; Siffel, C.; Piperakis, M. M. (2006)
      In this study we examine the effects of a mixture of pesticides on occupationally exposed agricultural workers. The study was performed on 149 people, 84 agricultural workers and 65 healthy men from the same area, who ...

    • The use of comet assay in measuring DNA damage and repair efficiency in child, adult, and old age populations 

      Piperakis, S. M.; Kontogianni, K.; Karanastasi, G.; Iakovidou-Kritsi, Z.; Piperakis, M. M. (2009)
      In the present study, we used the Comet assay to estimate basal DNA damage in three distinct populations aged 5-10, 40-50, and 60-70 years old. The DNA damage induced by hydrogen peroxide and gamma-irradiation in the ...